Category - Developments

Developments

First patients enrolled in Eyenovia Phase 3 MicroLine study for presbyopia

Eyenovia (NASDAQ:EYEN) announced that the first set of patients has been enrolled in the company’s Phase 3 VISION-1 study of MicroLine, a proprietary pilocarpine formulation delivered via its Optejet dispenser for the...

December 16, 2020

Developments

Verastem initiates Phase 2 non-small lung cancer trial

Verastem (NASDAQ:VSTM) initiated a Phase 2 registration-directed trial evaluating VS-6766 for the treatment of KRAS-G12V-mutant non-small cell lung cancer (NSCLC). In the first part of the study, VS-6766, a RAF/MEK...

December 15, 2020

Developments

Kiniksa Pharma initiates dosing in Phase 2b prurigo nodularis trial

Kiniksa Pharmaceuticals (NASDAQ:KNSA) initiated dosing in its Phase 2b trial evaluating vixarelimab for the treatment of prurigo nodularis. Prurigo nodularis is a skin disease that causes hard, itchy nodules to form on...

December 15, 2020

Developments

Aerpio reports positive topline results from Phase 2 glaucoma trial

Aerpio Pharma (NASDAQ:ARPO) reported positive topline results from its Phase 2 trial evaluating razuprotafib for the treatment of elevated intraocular pressure (IOP). The study enrolled 194 patients with elevated IOP...

December 14, 2020

Developments

Prevail Therapeutics doses first patient in Phase 1/2 frontotemporal dementia trial

Prevail Therapeutics (NASDAQ:PRVL) dosed the first patient in its Phase 1/2 PROCLAIM trial evaluating PR006 for the treatment of frontotemporal dementia patients with GRN mutations. Frontotemporal dementia is the second...

December 11, 2020

Developments

Geron begins enrollment in Phase 3 refractory myelofibrosis trial

Geron (NASDAQ:GERN) reported that its Phase 3 IMpactMF clinical trial, which is evaluating imetelstat for the treatment of refractory myelofibrosis, is open for patient screening and enrollment. The trial is designed to...

December 11, 2020

Developments

Lexicon gets FDA fast track designation for diabetic peripheral neuropathic pain

Lexicon Pharmaceuticals’ (NASDAQ:LXRX) LX9211 received FDA fast track designation for the treatment of diabetic peripheral neuropathic pain. The company is currently enrolling patients with diabetic peripheral...

December 11, 2020

Developments

Hepion completes 75 mg CRV431 dosing, initiates 225 mg dosing in AMBITION trial

Hepion Pharmaceuticals (NASDAQ:HEPA) completed patient dosing in the 75 mg cohort of its Phase 2a ‘AMBITION’ clinical trial, which is evaluating CRV431 for the treatment of non-alcoholic steatohepatitis (NASH). In...

December 10, 2020

Developments

Savara’s AeroVanc fails Phase 3 cystic fibrosis trial

Savara (NASDAQ:SVRA) reported that its Phase 3 AVAIL trial evaluating AeroVanc for the treatment of cystic fibrosis failed to meet its primary endpoint. The trial enrolled 55 cystic fibrosis patients with methicillin...

December 10, 2020

Developments

TG Therapeutics reports positive topline results from 2 Phase 3 MS trials

TG Therapeutics (NASDAQ:TGTX) reported positive topline data from its two Phase 3 trials evaluating ublituximab, an anti-CD20 monoclonal antibody, for the treatment of relapsing forms of multiple sclerosis (MS)...

December 10, 2020

Category - Developments

First patients enrolled in Eyenovia Phase 3 MicroLine study for presbyopia

Verastem initiates Phase 2 non-small lung cancer trial

Kiniksa Pharma initiates dosing in Phase 2b prurigo nodularis trial

Aerpio reports positive topline results from Phase 2 glaucoma trial

Prevail Therapeutics doses first patient in Phase 1/2 frontotemporal dementia trial

Geron begins enrollment in Phase 3 refractory myelofibrosis trial

Lexicon gets FDA fast track designation for diabetic peripheral neuropathic pain

Hepion completes 75 mg CRV431 dosing, initiates 225 mg dosing in AMBITION trial

Savara’s AeroVanc fails Phase 3 cystic fibrosis trial

TG Therapeutics reports positive topline results from 2 Phase 3 MS trials

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