Rein Therapeutics (NASDAQ: RNTX) has announced that the first patient has been dosed in its Phase 2 clinical trial evaluating LTI-03 for idiopathic pulmonary fibrosis (IPF), a progressive and fatal lung disease with limited treatment options.
According to Rein, this milestone follows the FDA’s recent clearance to resume the Phase 2 program and reflects Rein’s successful efforts to address the agency’s requests and advance the trial.
In a statement, Brian Windsor, PhD, CEO of Rein, commented, “Dosing the first patient in this Phase 2 trial marks an important step forward for Rein and, more importantly, for patients living with IPF. Current therapies offer limited benefit and often come with significant side effects. Our goal with LTI-03 is to go beyond slowing disease progression and help preserve lung function by addressing the underlying biology of fibrosis. This milestone reflects our team’s focus on execution and brings us closer to understanding the potential impact of LTI-03 for patients.”
