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Entera reports robust data for pipeline programs in HypoPT and obesity

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Entera Bio (NASDAQ: ENTX) has reported preclinical data at ENDO 2026, the annual meeting of the Endocrine Society, for its pipeline programs—EB612 in hypoparathyroidism (HypoPT) and EB618 in obesity and metabolic disorders—being co-developed with OPKO Health (NASDAQ: OPK).

In a poster presentation, among other data Entera highlighted: EB612 produced robust bioavailability and sustained increases in calcium across three preclinical models; and EB618 showed dose-proportional pharmacokinetics and a robust effect on blood glucose in non-human primates.

In a statement, Miranda Toledano, CEO of Entera, commented, “The strength of these results underscores the consistency of our N-Tab platform to develop proprietary oral peptides across a myriad of targets and indications.”

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